Which of the headers are better for 2.2 ecotec, 4 1 or 4 2 1
No HeaderS at all, its header and there is no best. Its all a personal preference, I like the 4-1 and other like 4-2-1. I think our cars have enough bottom end and no top end at all, so thats why I like the 4-1. 4-1= top end 4-2-1= bottom end.
2012 HD VRSCF
2010 Ford Explorer
2006 Ford Ranger
2004 Chevy Cavalier
Weapon-R makes a 4-2-1 header, as well, for the Ecotec. And like the others said, its all based on personal preference and personal needs. A 4-1 header will give you better top end power while a 4-2-1 header will give you more low-mid range power.

Blown.
I have 4-1 and really like the exhaust note and power above 4000 RPM